Getting My SANGE To Work
Getting My SANGE To Work
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Grupa sanguină a unui individ rămâne neschimbată pe parcursul vieții, cu excepția cazurilor de transplant de măduvă sau prin adiția sau dispariția unor antigene în infecții, boli maligne sau boli autoimune, ce pot implica schimbarea grupei de sânge. După cum se observă, la un individ nu se pot găsi antigenul și aglutinina corespunzătoare. Serul fiecărui individ conține anticorpi împotriva antigenelor treatment nu există pe eritrocitele sale. Dacă antigenul eritrocitar intră în Make contact with cu anticorpul certain, se make aglutinarea (agregare) și liza hematiilor.
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Aglutinogenele A și B prezintă mai multe variante, codificate genetic, importanță având subgrupele antigenului A, mai precis două dintre acestea: A1 (cuprinde aproximativ eighty% din indivizii grupei A) și A2 (cuprinde twenty% din indivizii grupei). Principala diferență dintre cele două grupe este că prezența genei A1 encounter ca transformarea substanței H în antigen A să fie aproape completă, iar gena A2 reworkă doar parțial antigenul H.
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